BOUNDED AND CATEGORIZED: TARGETING DATA ASSIMILATION FOR SEA ICE FRACTIONAL COVERAGE AND NONNEGATIVE QUANTITIES IN A SINGLE-COLUMN MULTI-CATEGORY SEA ICE MODEL

Bounded and categorized: targeting data assimilation for sea ice fractional coverage and nonnegative quantities in a single-column multi-category sea ice model

A rigorous exploration of the sea ice data assimilation (DA) problem using a framework specifically developed for rapid, interpretable hypothesis testing is presented.In many applications, DA is implemented to constrain a modeled estimate of a state with observations.The sea ice DA application is complicated by the wide range of spatiotemporal scal

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Fatal case of donor-derived colistin-resistant carbapenemase-producing Klebsiella pneumoniae transmission in cardiac transplantation

Herein we report a fatal case of donor-derived transmission of XDR-resistant carbapenemase-producing Klebsiella pneumoniae (KPC-Kp) in cardiac transplantation.A 59-year-old male patient with non-obstructive BLUEBERRY CONC hypertrophic cardiomyopathy underwent heart transplantation.On day 5 post-operation, blood cultures from the donor were positive

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Novel Approaches to Studying SLC13A5 Disease

The role of the sodium citrate transporter (NaCT) SLC13A5 is multifaceted and context-dependent.While aberrant dysfunction leads to neonatal epilepsy, its therapeutic inhibition protects against metabolic disease.Notably, insights regarding the cellular and molecular mechanisms underlying these Chemical Dispenser phenomena are limited due to the in

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